People may experience pain relief that can occur shortly after taking an NSAID , but it can take weeks for the inflammation to go away. When prostaglandins reach the brain, they can cause fever that naproxen and ibuprofen can also treat. By blocking the enzyme that produces prostaglandins, NSAIDs can impair platelet activity, hindering blood clots from forming.
However, some people should not take ibuprofen, such as those who are taking aspirin for heart protection. People may use NSAIDs for a short period early in rheumatoid arthritis, while other medications take effect. Naproxen is available in two forms: Naproxen and naproxen sodium. The body absorbs naproxen sodium better than naproxen.
Doses are in milligrams mg in the table below:. Although available over the counter, naproxen and ibuprofen may not be safe for people with the following conditions:. People who take prescription naproxen or ibuprofen may have increased risks for:.
The risk of cardiovascular events, clots, heart attack, and stroke may be higher in people with a history of cardiovascular disease or risk factors for cardiovascular disease. If taking NSAIDs within 2 weeks after heart surgery, people may be at an increased risk for heart attack and stroke. People who take naproxen or ibuprofen may have a greater risk of developing high blood pressure , heart failure , and water retention.
Older adults are more vulnerable to these severe side effects. People who take over-the-counter naproxen and ibuprofen at the labeled dose for 7—10 days may not have an increased risk of adverse effects. To minimize the risk for these adverse effects, people should take naproxen or ibuprofen at the lowest dose for the shortest length of time.
Some of these risks include an increased likelihood to experience a cardiovascular event like stroke or myocardial infarct, increased blood pressure and increased gastrointestinal bleeding. Though some studies have reported that Ibuprofen may have a slightly higher risk than Naproxen to cause adverse events, Naproxen cannot be considered a safer drug because the significant risks have still been reported with Naproxen.
Patients with chronic health conditions should check with their doctor or other health care provider before taking these drugs. Jennifer Hauder is a registered pharmacist in the state of Illinois. She has over 10 years experience as a pharmacist in the retail and pharmacy benefit managers PBM settings.
She became a pharmacist due to her interest in healthcare and the opportunity to help others with their healthcare needs. When not working, she enjoys spending time with her husband, three children and two black labs Lucky and Charms.
Ibuprofen vs. What ibuprofen and naproxen do. Side effects. Use with other conditions. Read this next. Medically reviewed by Alan Carter, Pharm. Medically reviewed by Zara Risoldi Cochrane, Pharm. Effects of Using Ibuprofen with Alcohol.
Acetaminophen: How Are They Different? Medically reviewed by Lindsay Slowiczek, PharmD. Medically reviewed by Debra Rose Wilson, Ph. Our Patient Communication Coordinators can help you find the right fit. Call These medications are commonly used as cure-alls. But each one can offer relief for certain symptoms and at different ages.
The first line of defense for your aches, pains and general unrest is the medicine cabinet. Once you start feeling under the weather, you pop a pill or two of acetaminophen, ibuprofen or naproxen. And before you know it — relief! Not at all, actually. While these over-the-counter drugs provide similar results, they are not the same.
Ibuprofen and naproxen can do both those things, but they are anti-inflammatory drugs designed to reduce inflammation and swelling. The lines are blurred. Acetaminophen, ibuprofen and naproxen have different chemical makeups, but the choice between them is not always clear. Depending on your condition, one is typically better suited than the other. When in doubt, use this guide to help you figure out which medicine to take. Naproxen and ibuprofen also have their differences.
Naproxen provides long-acting relief, so doses are taken just twice a day. Ibuprofen is a short-acting anti-inflammatory that can be taken every six to eight hours — the same dosing schedule as acetaminophen. Make an Appointment. Although acetaminophen, ibuprofen and naproxen are all over-the-counter medications, they are not entirely risk-free.
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