Due to these required multiple daily doses, T3 levels fluctuate in the body; when T3 levels are high, symptoms of hyperthyroidism often occur. Symptoms of hyperthyroidism include a fast heart rate, insomnia, and anxiety. A type of heart arrhythmia called atrial fibrillation and bone loss osteoporosis may also occur. Two such preparations available in the United States are:. Many experts, however, do not see these options as being the same as taking T4 and T3 independently.
Natural desiccated thyroid NDT hormone is a drug derived mainly from the dried glands of pigs. Moreover, the amounts of T4 and T3 can vary from batch to batch of NDT—and this can affect the stability of thyroid hormone levels in your body. However, this high dose of T3 can cause symptoms of hyperthyroidism. When taking T3, it's simply impossible to avoid "T3 spikes," which can lead to unpleasant hyperthyroid symptoms, like anxiety or a rapid heart rate.
Research suggests that a subgroup of hypothyroid patients on levothyroxine continue to have symptoms fatigue, difficulty losing weight, etc. Excess T3 in a pregnant woman may cause hypothyroxinemia in the developing fetus, which is associated with potential neurological problems. The big picture for you or a loved one is to understand that, as of now, the standard treatment for hypothyroidism is a T4 drug alone.
Though the addition of T3 continues to be a topic of ongoing research and debate within the thyroid community, for certain patients, it may be a sensible strategy. Right now, the best thing you can do for your thyroid care is to carefully talk through your options with your healthcare provider.
Remember, as well, that optimizing your thyroid hormone levels can be a trial and error process—especially in the beginning. Try to remain patient as your treatment plan is honed. Losing weight with thyroid disease can be a struggle. Our thyroid-friendly meal plan can help. Sign up and get yours free! American Thyroid Association. Hypothyroidism FAQS. Thyroid hormone treatment. Updated June Dayan C, Panicker V. Management of hypothyroidism with combination thyroxine T4 and triiodothyronine T3 hormone replacement in clinical practice: a review of suggested guidance.
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Hashimoto's , Natural Remedies , Thyroid Thrivers. We lowered the dose of levothyroxine T4 moderately and I started taking a small amount of compounded T3 every 12 hours.
It was like the sun came up! I have much more energy and all my typical hypothyroidism symptoms abated. You are not the only patient who has been unhappy with levothyroxine T4-only treatment of hypothyroidism. A recent online survey of more than 12, individuals with hypothyroidism found that those taking levothyroxine alone were least satisfied with their results Peterson et al, Thyroid , online April 5, People taking a combination of T4 with T3, as you do, were better pleased with their treatment, while those taking desiccated thyroid extract, such as Armour, reported the fewest problems with weight control, fatigue, mood and memory.
This natural pork extract contains both T3 and T4, though not in the same proportions as human thyroid glands. The body converts T4 to the active hormone T3 by removing one molecule of iodine. They deserve treatment that includes T3 with T4 so that they can feel well.
You can learn more about these controversies, interpretation of lab results and treatment options in our online Guide to Thyroid Hormones.
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